Democracy Dies in Darkness

An AI blood test purports to diagnose postpartum depression

Companies are using artificial intelligence to take aim at a host of health issues including this common pregnancy complication.

April 29, 2024 at 8:00 a.m. EDT
(Shutterstock)
6 min
correction

A previous version of this article incorrectly stated that Dionysus Digital Health received a $6 billion grant from the Department of Defense. It received $6 million.

Postpartum depression is a leading cause of maternal death, but its diagnosis and treatment is spotty at best, negligent at worst.

Now San Diego-based start-up Dionysus Digital Health is pitching a blood test to check for the condition, even before symptoms appear. The company says it has pinpointed a gene linking a person’s moods more closely to hormonal changes. The test uses machine learning to compare epigenetics — how genes are expressed — in a blood sample with benchmarks developed during a decade of research into pregnant people who did and didn’t develop postpartum depression.